Prof. Dr. Kalina Peneva

Funktionen

• STIFT Professur für Funktionale Farbstoffe, Maker und molekulare Sensoren

Forschungsgebiete

• Synthesis, characterization and evaluation of fluorophores, smal therapeutically active molecule and chemically defined carriers that find application in drug delivery, nanomedicine and biosensing
• Synthesis and characterization of biocompatible polymeric carriers for siRNA
• Water-soluble rylene dyes for biomedical applications
• Bioconjugation and site-selective modification of proteins

Publikationen (die 10 wichtigsten)

1. Kaloyanova, Y. Zagranyarski, S. Ritz, M. Hanulova, K. Koynov, A. Vonderheit, K. Muellen, K. Peneva, "Water-soluble NIR-absorbing rylene chromophores for selective staining of cellular organelles" J. Am. Chem. Soc. 2016, 138, 2881-2884.
2. Lelle, S. Kaloyanova, C. Freidel, M. Theodoropoulou, M. Musheev, C. Niehrs, G. Stalla, K. Peneva, "Octreotide-mediated tumor-targeted drug delivery via cleavable doxorubicin-peptide conjugate", Mol. Pharm. 2015, 12, 4290-4300.
3. Freidel, S. Kaloyanova, K. Peneva, "Chemical tags for site-specific fluorescent labelling of biomolecules", Amino Acids 2016, 48, 1357-1372.
4. Kantner, S. Ashraf, P. del Pino, W. Heimbrodt, K. Dorleta, L. Kazakova, M. Lelle, J. M. Montenegro, K. Peneva, S. Nadeem, L. Schneider, G. B. Sukhorukov, F. Yang, W. J. Parak, "Particle-based optical sensing of intracellular ions at the example of calcium - What are the experimental pitfalls?" Small 2015, 8, 896-904.
5. Tsoneva, H. Jonker, M. Wagner, A. Tadjer, M. Lelle, K. Peneva, A. Ivanova, "Molecular structure and pronounced conformational flexibility of doxorubicin in free and conjugated state within a drug-peptide complex", J. Phys. Chem. B 2015, 119, 3001-3013.
6. Krieg, M. Hirsch, E. Scholz, L. Nuhn, I. Tabujew, H. Bauer, S. Decker, A. Khobta, M. Schmidt, W. Tremel, R. Zentel, K. Peneva, K. Koynov, A. J. Mason, M. Helm, "New techniques to assess in vitro release of siRNA from nanoscale polyplexes", Pharm. Res. 2015, 32, 1957-1974.
7. Tabujew, C. Freidel, B. Krieg, M. Helm, K. Koynov, K. Müllen, K. Peneva, "The guanidinium group as a key part of water-soluble polymer carriers for siRNA complexation and protection against degradation", Macromol. Rapid Commun. 2014, 35, 1191-1197.
8. Dorresteijn, R. Ragg, G. Rago, N. Billecke, M. Bonn, S. Parekh, G. Battagliarin, K. Peneva, M. Wagner, M. Klapper, K.  Muellen, "Biocompatible polylactide-block-polypeptide-block-polylactide nanocarrier" Biomacromolecules 2013, 5, 1525-1577.
9. Peneva, K. Gundlach, A. Herrmann, H. Paulsen, K. Muellen, "Site-specific incorporation of perylene into an N-terminally modified light-harvesting complex II", Org. Biomol. Chem. 2010, 8, 4823-4826.
10. Weil, T. Vosch, J. Hofkens, K. Peneva, K. Muellen, "The rylene colorant family-tailored nanoemitters for photonics research and applications", Angew. Chem. Int. Ed. 2010, 49, 9068-9093.