Institut für Organische Chemie und Makromolekulare Chemie (IOMC) Friedrich-Schiller-Universität Jena Lessingstraße 8 07743 Jena Telefon: +49 3641 9 48 790 Telefax: +49 3641 9 48 792 kalina.peneva@uni-jena.de Homepage en
Funktionen
STIFT Professur für Funktionale Farbstoffe, Maker und molekulare Sensoren
Forschungsgebiete
Synthesis, characterization and evaluation of fluorophores, smal therapeutically active molecule and chemically defined carriers that find application in drug delivery, nanomedicine and biosensing
Synthesis and characterization of biocompatible polymeric carriers for siRNA
Water-soluble rylene dyes for biomedical applications
Bioconjugation and site-selective modification of proteins
Publikationen (die 10 wichtigsten)
Kaloyanova, Y. Zagranyarski, S. Ritz, M. Hanulova, K. Koynov, A. Vonderheit, K. Muellen, K. Peneva, "Water-soluble NIR-absorbing rylene chromophores for selective staining of cellular organelles" J. Am. Chem. Soc.2016, 138, 2881-2884.
Lelle, S. Kaloyanova, C. Freidel, M. Theodoropoulou, M. Musheev, C. Niehrs, G. Stalla, K. Peneva, "Octreotide-mediated tumor-targeted drug delivery via cleavable doxorubicin-peptide conjugate", Mol. Pharm.2015, 12, 4290-4300.
Freidel, S. Kaloyanova, K. Peneva, "Chemical tags for site-specific fluorescent labelling of biomolecules", Amino Acids2016, 48, 1357-1372.
Kantner, S. Ashraf, P. del Pino, W. Heimbrodt, K. Dorleta, L. Kazakova, M. Lelle, J. M. Montenegro, K. Peneva, S. Nadeem, L. Schneider, G. B. Sukhorukov, F. Yang, W. J. Parak, "Particle-based optical sensing of intracellular ions at the example of calcium - What are the experimental pitfalls?" Small2015, 8, 896-904.
Tsoneva, H. Jonker, M. Wagner, A. Tadjer, M. Lelle, K. Peneva, A. Ivanova, "Molecular structure and pronounced conformational flexibility of doxorubicin in free and conjugated state within a drug-peptide complex", J. Phys. Chem. B2015, 119, 3001-3013.
Krieg, M. Hirsch, E. Scholz, L. Nuhn, I. Tabujew, H. Bauer, S. Decker, A. Khobta, M. Schmidt, W. Tremel, R. Zentel, K. Peneva, K. Koynov, A. J. Mason, M. Helm, "New techniques to assess in vitro release of siRNA from nanoscale polyplexes", Pharm. Res.2015, 32, 1957-1974.
Tabujew, C. Freidel, B. Krieg, M. Helm, K. Koynov, K. Müllen, K. Peneva, "The guanidinium group as a key part of water-soluble polymer carriers for siRNA complexation and protection against degradation", Macromol. Rapid Commun.2014, 35, 1191-1197.
Dorresteijn, R. Ragg, G. Rago, N. Billecke, M. Bonn, S. Parekh, G. Battagliarin, K. Peneva, M. Wagner, M. Klapper, K. Muellen, "Biocompatible polylactide-block-polypeptide-block-polylactide nanocarrier" Biomacromolecules2013, 5, 1525-1577.
Peneva, K. Gundlach, A. Herrmann, H. Paulsen, K. Muellen, "Site-specific incorporation of perylene into an N-terminally modified light-harvesting complex II", Org. Biomol. Chem.2010, 8, 4823-4826.
Weil, T. Vosch, J. Hofkens, K. Peneva, K. Muellen, "The rylene colorant family-tailored nanoemitters for photonics research and applications", Angew. Chem. Int. Ed.2010, 49, 9068-9093.