Institute of Nutrition Department of Biochemistry and Nutrition Friedrich Schiller University Jena Dornburger Straße 25 07743 Jena Phone: +49 3641 9 49 710 Fax: +49 3641 9 49 712 email@example.com Homepage
Professor of Biochemistry of Nutrition
Head of Department "Biochemistry of Nutrition"
Transfection and transduction of monocytes and macrophages
Heterozygosity of monocytes and plasticity of macrophages
Molecular basis of atherosclerosis and inflammation
Nutritive modulation of lipid metabolism and cellular lipid metabolism / transport
Molecular mechanisms of action of nutritional constituents
Publications (the 10 most important)
Rennert, K. Heisig, M. Groeger, M. Wallert, H. Funke, S. Lorkowski, O. Huber, A. S. Mosig, "Recruitment of CD16(+) monocytes to endothelial cells in response to LPS-treatment and concomitant TNF release is regulated by CX3CR1 and interfered by soluble fractalkine", Cytokine2016, 83, 41-52.
Raasch, K. Rennert, T. Jahn, S. Peters, T. Henkel, O. Huber, I. Schulz, H. Becker, S. Lorkowski, H. Funke, A. Mosig, "Microfluidically supported biochip design for culture of endothelial cell layers with improved perfusion conditions", Biofabrication2015, 7, 015013.
Scherer, M.B. Maeß, S. Lindner, U. Garscha, C. Weinigel, S. Rummler, O. Werz, S. Lorkowski, "A procedure for efficient non-viral siRNA transfection of primary human monocytes using nucleofection", J. Immunol. Methods2015, 422, 118-124.
B. Maeß, A. A. Keller, K. Rennert, A. Mosig, S. Lorkowski, "Optimization of the transfection of human THP-1 macrophages by application of Nunc UpCell technology", Anal. Biochem.2015, 479, 40-42.
B. Maeß, B. Wittig, S. Lorkowski, "Highly efficient transfection of human THP-1 macrophages by nucleofection", J. Vis. Exp.2014, 91, e51960.
Stiebing, C. Matthäus, C. Krafft, A. A. Keller, K. Weber, S. Lorkowski, J. Popp, "Complexity of fatty acid distribution inside human macrophages on single cell level using Raman micro-spectroscopy", Anal. Bioanal. Chem.2014, 406, 7037-7046.
A. Keller, F. Mussbach, R. Breitling, P. Hemmerich, B. Schaefer, S. Lorkowski, S. Reissmann, "Relationships between cargo, cell penetrating peptides and cell type for uptake of non-covalent complexes into live cells", Pharmaceuticals2013, 6, 184-203.
B. Maess, I. Buers, H. Robenek, S. Lorkowski, "Improved protocol for efficient nonviral transfection of premature THP-1 macrophages", Cold Spring Harbor Protoc.2011, 2011, 508-511.
Robenek, I. Buers, O. Hofnagel, S. Lorkowski, N. J. Severs, "GFP-tagged proteins visualized by freeze-fracture immuno-electron microscopy: A new tool in cellular and molecular medicine", J. Cell. Mol. Med.2009, 13, 1381-1390.
Schnoor, P. Cullen, J. Lorkowski, K. Stolle, H. Robenek, D. Troyer, J. Rauterberg, S. Lorkowski, "Production of type VI collagen by human macrophages: A new dimension in macrophage functional heterogeneity", J. Immunol.2008, 180, 5707-5719.