Director of the Institute for Medical Microbiology, UKJ
Member of the Board of Directors of the Interdisciplinary Center for Clinical Research (IZKF) of the UKJ Jena
Member of the Board of the Center for Sepsis Control and Care (CSCC) with promotion of young scientists
Member of the Jena School for Microbial Communication (JSMC)
Toxin-mediated effects in bacterial infections and viral-bacterial co-infections
Persistence strategies of pathogens
Infection models and testing of therapy strategies
Publications (the 5 most important)
B. Löffler, M. Hussain, M. Grundmeier, M. Bruck, D. Holzinger, G. Varga, J. Roth, B. C. Kahl, R. A. Proctor, G. Peters, Staphylococcus aureus panton-valentine leukocidin is a very potent cytotoxic factor for human neutrophils. PLoS Pathog 2010, 6:e1000715.
L. Tuchscherr, E. Medina, M. Hussain, W. Völker, V. Heitman, S. Niemann, D. Holzinger, J. Roth, R. A. Proctor, K. Becker, G. Peters, B. Löffler, Staphylococcus aureus phenotype switching: an effective bacterial strategy to escape host immune response and establish a chronic infection. EMBO Mol Med 2011, 3:129-141.
J. Wang, Y. Morita, B. Han, S. Niemann, B. Löffler, K. L. Rudolph, Per2 induction limits lymphoid-biased haematopoietic stem cells and lymphopoiesis in the context of DNA damage and ageing. Nat Cell Biol 2016, 18:480-490.
B. C. Kahl, K. Becker, B. Löffler, Clinical Significance and Pathogenesis of Staphylococcal Small Colony Variants in Persistent Infections. Clin Microbiol Rev 2016, 29:401-427
S. Deinhardt-Emmer, K. Rennert, E. Schicke, Z. Cseresnyes, M. Windolph, S. Nietzsche, R. Heller, F. Siwczak, K. F. Haupt, S. Carlstedt, M. Schacke, M. T. Figge, C. Ehrhardt, B. Löffler, A. S. Mosig, Co-infection with Staphylococcus aureus after primary influenza virus infection leads to damage of the endothelium in a human alveolus-on-a-chip model. Biofabrication 2020 12:025012.