Dr. Joachim Clement

Functions

• Research Group Leader Hematology and Internal Oncology

Research

• Innovative nanomaterials in biomedicine
• Identification and characterization of circulating tumor cells and Tomor associated cells
• Tumor biology of bone morphogenesis factors

Publications (the 5 most important)

1. Clement, J.H., Schwalbe, M., Buske, N., Wagner, K., Schnabelrauch, M., Görnert, P., Kliche, K.O., Pachmann, K., Weitschies W., Höffken, K. 2006. Differential interaction of magnetic nanoparticles with tumor cells and peripheral blood cells. J. Cancer Res. Clin. Oncol. 132: 287-292.
2. Neugebauer, U., Bocklitz, T., Clement, J.H., Krafft, C., Popp, J. 2010. Towards Detection and Identification of Circulating Tumour Cells using Raman Spectroscopy. Analyst 135: 3178 - 3182.
3. Weiss, J., Sos, M.L., Seidel, D., Peifer, M., Zander, T., Heuckmann, J.M., Ullrich, R.T., Menon, R., Maier, S., Soltermann, A., Moch, H., Wagener, P., Fischer, F., Heynck, S., Koker, M., Schöttle, J., Leenders, F., Gabler, F., Dabow, I., Querings, S., Heukamp, L.C., Balke-Want, H., Ansén, S., Rauh, D., Baessmann, I., Altmüller, J., Wainer, Z., Conron, M., Wright, G., Solomon, B., Brambilla, E., Brambilla, C., Lorimier, P., Sollberg, S., Brustugun, O.T., Engel-Riedel, W., Corinna Ludwig, C., Petersen, I., Sänger, J., Clement, J.H., Groen, H., Timens, W., Sietsma, H., Thunnissen, E., Smit, E., Heideman, D., Cappuzzo, F., Ligorio, C., Damiani, S., Beroukhim, R., Pao, W., Klebl, B., Baumann, M., Buettner, R., Ernestus, K., Stoelben, E., Wolf, J., Nürnberg, P., Perner, S. und Thomas, R.K. 2010. Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer. Science Transl Med 2: 62ra93
4. Gottschaldt, M., Schubert, U.S., Rau, S., Yano, S., Vos, J.G., Kroll, T., Clement, J.H., Hilger, I. 2010. Sugar-Selective Enrichment of D-Glucose Substituted Ruthenium Bipyridyl Complex Inside HepG2 Cancer Cells. ChemBioChem 11: 649-652.
5. Steinert, S., Kroll, T.C., Taubert, I., Pusch, L., Hortschansky, P., Höffken, K., Wölfl, S. und Clement, J.H. 2008. Differential expression of cancer related genes by single and permanent exposure to bone morphogenetic protein 2 (BMP-2). J. Cancer Res. Clin. Oncol. 134: 1237-1245