Research Group Leader Hematology and Internal Oncology
Research
Innovative nanomaterials in biomedicine
Identification and characterization of circulating tumor cells and Tomor associated cells
Tumor biology of bone morphogenesis factors
Publications (the 5 most important)
Clement, J.H., Schwalbe, M., Buske, N., Wagner, K., Schnabelrauch, M., Görnert, P., Kliche, K.O., Pachmann, K., Weitschies W., Höffken, K. 2006. Differential interaction of magnetic nanoparticles with tumor cells and peripheral blood cells. J. Cancer Res. Clin. Oncol.132: 287-292.
Neugebauer, U., Bocklitz, T., Clement, J.H., Krafft, C., Popp, J. 2010. Towards Detection and Identification of Circulating Tumour Cells using Raman Spectroscopy. Analyst135: 3178 - 3182.
Weiss, J., Sos, M.L., Seidel, D., Peifer, M., Zander, T., Heuckmann, J.M., Ullrich, R.T., Menon, R., Maier, S., Soltermann, A., Moch, H., Wagener, P., Fischer, F., Heynck, S., Koker, M., Schöttle, J., Leenders, F., Gabler, F., Dabow, I., Querings, S., Heukamp, L.C., Balke-Want, H., Ansén, S., Rauh, D., Baessmann, I., Altmüller, J., Wainer, Z., Conron, M., Wright, G., Solomon, B., Brambilla, E., Brambilla, C., Lorimier, P., Sollberg, S., Brustugun, O.T., Engel-Riedel, W., Corinna Ludwig, C., Petersen, I., Sänger, J., Clement, J.H., Groen, H., Timens, W., Sietsma, H., Thunnissen, E., Smit, E., Heideman, D., Cappuzzo, F., Ligorio, C., Damiani, S., Beroukhim, R., Pao, W., Klebl, B., Baumann, M., Buettner, R., Ernestus, K., Stoelben, E., Wolf, J., Nürnberg, P., Perner, S. und Thomas, R.K. 2010. Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer. Science Transl Med 2: 62ra93
Gottschaldt, M., Schubert, U.S., Rau, S., Yano, S., Vos, J.G., Kroll, T., Clement, J.H., Hilger, I. 2010. Sugar-Selective Enrichment of D-Glucose Substituted Ruthenium Bipyridyl Complex Inside HepG2 Cancer Cells. ChemBioChem11: 649-652.
Steinert, S., Kroll, T.C., Taubert, I., Pusch, L., Hortschansky, P., Höffken, K., Wölfl, S. und Clement, J.H. 2008. Differential expression of cancer related genes by single and permanent exposure to bone morphogenetic protein 2 (BMP-2). J. Cancer Res. Clin. Oncol.134: 1237-1245